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Bioactive Compounds from Natural Sources: Isolation Corrado Tringali, Ebooks Corporation.
Publisher: CRC Press

Marine microbes have received growing attention as the sources for bioactive metabolites and have great potential to increase the number of marine natural products in clinical trials. Lead compounds with biomedical potential have been isolated from marine invertebrates, bacteria, and fungi. Many marine natural products are potentially therapeutic. The work offers a sustainable way to supply marine natural products for human use. In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiting anti-cancer potential both in vitro and in vivo. Plant triterpenoids represent a large and structurally diverse class of natural products. For example, β-elemene, a compound isolated from Curcuma wenyujin Y. Medicinal herbs are main sources of new drugs. Ling (Wenyujin), is used as an anti-cancer drug in China. Team led by Se-Kwon Kim from Pukyong National University noted that the last decade has seen 'numerous' novel compounds to be isolated from marine organisms, “and many of these compounds are potential for industrial development of functional foods. The Korean researchers noted that natural seaweed compound has been generating 'a great deal' of interest parts of the industry as consumers begin to develop interest in functional foods from natural sources. Each year numerous compounds with an array of biological activities are reported, but and a metabolite isolated from a tunicate. Finally, attention was also paid to sterols and triterpenoids in callus cultures, a potential readily available source of bioactive compounds. During these last ten years, triterpenoids isolated from a large number of plant organs from different species have been reported to exhibit a variety of antimicrobial, antioxidant, anti-inflammatory, antiviral, or antitumor-promoting biological activities [5–7].